INFOMAK CV 625 is a combination antibiotic containing Amoxicillin 500 mg and Clavulanic Acid 125 mg. Amoxicillin is a well-established penicillin-class antibiotic that inhibits bacterial cell-wall synthesis. Clavulanic acid is a β-lactamase inhibitor that protects amoxicillin from destruction by β-lactamase enzymes produced by many resistant bacteria, restoring and extending amoxicillin’s effectiveness. Together they provide powerful, broad-spectrum antibacterial coverage for a variety of community and some hospital infections when used as directed by a physician.

Uses / Indications

• Acute bacterial sinusitis and otitis media

• Lower and upper respiratory tract infections (bronchitis, community-acquired pneumonia)

• Skin and soft tissue infections

• Urinary tract infections (uncomplicated)

• Bite wounds and certain dental infections

• Other infections where the causative bacteria are susceptible and a β-lactam/β-lactamase inhibitor is indicated

Key benefits

• Broad spectrum of activity against common pathogens

• Effective against many β-lactamase producing strains due to clavulanic acid protection

• Familiar, widely used antibiotic backbone (amoxicillin) with improved resistance profile

• Suitable for many common outpatient infections — shorter effective therapy when used appropriately

How INFOMAK CV 625 works

• Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, causing cell lysis.

• Clavulanic acid irreversibly inhibits β-lactamase enzymes produced by resistant bacteria, preventing destruction of amoxicillin and enabling it to kill those bacteria.

Dosage & how to take

• Prescription only. Follow your doctor’s dosing instructions. Typical adult dosing for INFOMAK CV 625 (tablet) is usually one tablet every 8–12 hours depending on infection severity and prescriber guidance.

• Complete the full prescribed course even if you feel better earlier to avoid relapse and resistance.

• Take with food to improve absorption and reduce stomach upset.

• If you miss a dose, take it as soon as you remember; do not double the next dose.

Note: Pediatric dosing, dosing for severe infections or renal impairment must be prescribed by a clinician — do not self-dose.

Common side effects

• Gastrointestinal: nausea, vomiting, diarrhea, abdominal discomfort. (Diarrhea is common — if severe or persistent, contact your doctor.)

• Hypersensitivity reactions: rash, urticaria. Serious allergic reactions (anaphylaxis) are rare but possible in penicillin-sensitive patients.

• Other: headache, dizziness, yeast infections (oral/vaginal) with prolonged use.

Serious but rare warnings

• Allergy: Do not take if you have a history of penicillin allergy or severe hypersensitivity to β-lactams. Seek immediate care for breathing difficulty, swelling or severe rash.

• Clostridioides difficile infection: Prolonged antibiotic use may lead to C. difficile colitis — report severe diarrhea, abdominal pain or fever to your doctor.

• Liver effects: Rare cases of hepatic dysfunction and cholestatic jaundice have been reported; stop medicine and consult doctor if you notice yellowing of skin/eyes, dark urine, severe fatigue.

• Renal impairment: Dose adjustments may be required in severe kidney disease.

Drug interactions & precautions

• Inform your doctor about all medicines you take — especially oral contraceptives (antibiotics can reduce efficacy), anticoagulants (monitor INR), allopurinol (higher incidence of rash), and certain other drugs.

• Caution when co-administering with bacteria-targeting bacteriostatic antibiotics (may reduce efficacy).

• Use with care in patients with history of severe allergy to penicillins or cephalosporins.

Contraindications

• Known hypersensitivity to amoxicillin, clavulanic acid, other penicillins or β-lactams.

• History of cholestatic jaundice or hepatic dysfunction associated with prior use of amoxicillin-clavulanate.

Storage

Store in a cool, dry place below 25–30°C. Protect from moisture and direct sunlight. Keep out of reach of children.

When to consult a doctor

• No improvement within 48–72 hours for many infections (or sooner for severe infections).

• Severe or persistent diarrhea, abdominal pain, jaundice, allergic reaction, breathing difficulty, high fever, or other worrying symptoms.

FAQ

1. Q: Is INFOMAK CV 625 safe for children?
   A: Pediatric dosing differs and depends on weight/age — do not give adult tablets to children. Consult a paediatrician for correct formulation and dose.

2. Q: Can I stop the medicine when I feel better?
   A: No — always complete the full prescribed course to prevent relapse and resistance.

3. Q: Does it affect oral contraceptives?
   A: Antibiotics may reduce the effectiveness of oral contraceptives in rare cases — use additional contraception while on therapy and for a short time after; consult your doctor.

4. Q: What should I do if I get diarrhea?
   A: Mild diarrhea is common; maintain hydration. If diarrhea is severe, bloody, or persistent, contact your doctor — it may signal C. difficile infection.

5. Q: Can I take it with food?
   A: Yes — taking INFOMAK CV 625 with food reduces stomach upset and is generally recommended.