PIROJAZ Injection is a parenteral NSAID preparation used for rapid relief of pain and inflammation in musculoskeletal and joint disorders. It is particularly beneficial in acute painful episodes of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and postoperative pain where oral administration is not possible or not suitable. Administered intramuscularly, it provides fast onset of action and symptomatic relief.
PIROJAZ Injection is indicated in the management of acute exacerbations of musculoskeletal and joint disorders such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, lumbago, sciatica, postoperative pain, and traumatic inflammation. It is used when a rapid onset of action is required and oral therapy is not feasible.
Piroxicam is a potent NSAID that inhibits the cyclooxygenase (COX-1 and COX-2) enzymes, reducing the synthesis of prostaglandins responsible for pain, swelling, and inflammation. By lowering prostaglandin levels, it alleviates pain, improves mobility, and reduces joint stiffness.
PIROJAZ Injection is given intramuscularly, usually in the gluteal muscle, by a qualified healthcare professional. The typical adult dose is one 20 mg injection once daily. The duration and frequency should be determined by the physician based on the condition and patient’s response. Use the lowest effective dose for the shortest possible duration to minimize risks.
Common side effects include injection site pain, gastrointestinal upset, nausea, abdominal discomfort, and dizziness. Serious risks include gastrointestinal bleeding, peptic ulceration, renal impairment, and cardiovascular events. Hypersensitivity reactions, including rash or bronchospasm, may occur. Report any severe abdominal pain, vomiting blood, black stools, swelling, chest pain, or breathing difficulties immediately.
Contraindicated in patients with hypersensitivity to piroxicam, other NSAIDs, or excipients in the formulation. Avoid in patients with active or recurrent peptic ulcer disease, gastrointestinal bleeding, severe hepatic or renal impairment, uncontrolled hypertension, or established heart failure. Contraindicated in late pregnancy due to risk of fetal harm. Elderly patients require cautious dosing due to higher risk of adverse effects.
Concomitant use with other NSAIDs, anticoagulants, antiplatelet agents, corticosteroids, ACE inhibitors, diuretics, or SSRIs increases the risk of gastrointestinal bleeding, renal impairment, or cardiovascular side effects. Always inform the prescriber of all medications being taken.
Store at a temperature below 25°C, protected from light and moisture. Do not freeze. Keep out of reach of children. Use only clear solutions and discard if the ampoule is damaged or discoloured.
Seek medical advice if severe abdominal pain, gastrointestinal bleeding, chest pain, shortness of breath, swelling of extremities, or severe allergic reactions occur. Consult your doctor if pain persists beyond the prescribed course.
Q1. What is PIROJAZ Injection used for?
It is used for rapid relief of pain and inflammation in arthritis, musculoskeletal conditions, and postoperative pain when oral NSAIDs are unsuitable.
Q2. How is PIROJAZ Injection given?
It is administered intramuscularly by a healthcare professional, usually in the gluteal region.
Q3. Can PIROJAZ Injection cause stomach problems?
Yes, like other NSAIDs it can cause gastritis, ulcers, or bleeding. Taking the lowest effective dose for the shortest period reduces this risk.
Q4. Is it safe for patients with heart problems?
Caution is advised, as NSAIDs may increase cardiovascular risks. Patients with hypertension, heart disease, or stroke history should use only under close medical supervision.
Q5. Can PIROJAZ Injection be used in pregnancy?
It is contraindicated in late pregnancy and should only be used if prescribed in earlier trimesters, when benefits outweigh risks.
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