RABMAN DSR is a combination medicine containing Domperidone 30 mg and Rabeprazole 20 mg in a DSR (delayed/sustained release) formulation. Rabeprazole reduces production of stomach acid by inhibiting the proton pump, helping heal acid-related damage (GERD, erosive oesophagitis, peptic ulcers) and relieving heartburn and regurgitation. Domperidone improves gastric motility and helps prevent or relieve nausea, vomiting and post-meal fullness by speeding up stomach emptying. Together they address both the cause (acid) and the symptoms (delayed emptying, nausea) for more complete symptomatic relief.

Uses / Indications

• Gastroesophageal reflux disease (GERD) and symptomatic heartburn

• Peptic/duodenal ulcer management and healing support

• Acid-related gastritis and dyspepsia (indigestion)

• Relief from nausea, vomiting and post-prandial fullness associated with delayed gastric emptying

• Adjunctive therapy where acid suppression plus improved gastric motility are required

Key benefits (bullet points)

• Dual action: reduces acid (Rabeprazole) and improves gastric emptying (Domperidone)

• Rapid symptom relief from heartburn, regurgitation and nausea

• DSR formulation supports sustained effect and convenient dosing

• Helps healing of acid-related lesions when used as prescribed

How RABMAN DSR works (mechanism)

• Rabeprazole (20 mg) — a proton-pump inhibitor (PPI) that blocks the final step of acid production in stomach parietal cells, lowering gastric acidity and allowing inflammation/erosions to heal.

• Domperidone (30 mg) — a dopamine D2 receptor antagonist that increases gastric motility and accelerates stomach emptying; it also acts on the chemoreceptor trigger zone to reduce nausea and vomiting.

Dosage & how to take

• Always follow your doctor’s prescription. Typical use: one DSR tablet daily or as directed.

• PPIs like rabeprazole are often taken before a meal (usually in the morning). Domperidone is commonly taken before meals to improve gastric emptying — follow physician instructions for combined formulation.

• Do not exceed the prescribed dose. If you miss a dose, take it as soon as you remember unless it is nearly time for the next dose.

Note: The exact dosing schedule for a combined DSR tablet may vary — always follow the prescribing information supplied by the physician or the product leaflet.

Side effects (common & important)

Most people tolerate RABMAN DSR well, but some may experience:

• Headache, dizziness

• Dry mouth, abdominal discomfort, bloating

• Diarrhea or constipation

• Rarely: allergic reactions, changes in liver enzymes, or extrapyramidal symptoms (uncommon with domperidone but possible)

• Domperidone can be associated with cardiac effects (QT prolongation) in susceptible people or when taken with interacting medicines — discuss your heart history with your doctor.

If you experience severe side effects (chest pain, fainting, irregular heartbeat, severe rash, jaundice, uncontrollable movements) stop and seek medical help immediately.

Warnings, contraindications & drug interactions

• Prescription medicine — do not self-medicate.

• Not suitable for patients with known hypersensitivity to rabeprazole, domperidone or any excipient.

• Avoid if you have known cardiac arrhythmias, prolonged QT interval, or are taking other QT-prolonging drugs (certain antiarrhythmics, some antipsychotics, macrolide antibiotics, etc.).

• Use caution (or avoid) with strong CYP3A4 inhibitors or drugs known to interact with domperidone or rabeprazole.

• Consult your doctor if you have liver disease, kidney disease, prolactinoma, or endocrine disorders.

• Not recommended during pregnancy or breastfeeding unless the doctor decides benefits outweigh risks — discuss with your clinician.

Precautions

• Inform your doctor about all other medicines you take (OTC, herbal, prescriptions).

• If symptoms persist or worsen after a short course, consult a physician — persistent heartburn or dyspepsia may need investigation.

• Long-term use of PPIs may be linked to increased risk of certain infections (e.g., C. difficile), decreased B12 absorption, and bone density changes — monitor per medical advice.

Storage

Store in a cool, dry place below 25–30°C. Protect from light and moisture. Keep out of reach of children.

When to consult a doctor

• Severe or persistent abdominal pain, unexplained weight loss, difficulty swallowing, persistent vomiting, or signs of bleeding (black stools/coffee-ground vomit).

• If you have heart disease, take other heart medicines, or are on multiple medications.